Advances in nuclear medicine in recent years have improved the study of biology, physiology, and pathophysiology. At the same time, it has also provided effective, and in some cases irreplaceable, means for diagnostic investigation and therapeutic action. Dynamic evaluation and morphological representation of organs and tissues are made possible by tracking techniques. The use of radioisotopes is of particular interest for the study of phenomena linked to the metabolism of many substances and for the detection and localisation of neoplastic processes. Through lectures, seminars and discussions, the school intends to explore the current possibilities offered by radioisotope investigations in this area of research and clinical diagnosis, and to assess foreseeable developments. Particular investigations to be carried out in order to achieve the best results while minimising patient exposure to ionising radiation will also be highlighted. In this latter regard, an important contribution can be made by developing the current body of knowledge acquired using gamma cameras and whole-body counters.